| Faculty
Name |
Department |
Description |
| Michael Been |
Professor of Biochemistry |
Mechanism and structure of autocatalytic RNA. |
| Lorena Beese |
Associate Professor of Biochemistry |
Structure and mechanism of proteins and macromolecular assemblies central to DNA replication, DNA repair, and cellular signaling. X-ray crystallography. Structure-based drug design. Cancer biology. |
| Perry Blackshear |
Adjunct Professor of Biochemistry |
Protein phosphorylation and biosynthesis in the action of hormones and cell growth. |
| Patrick Casey |
Professor
of Pharmacology
and Cancer Biology |
Cellular signalling mediated through GTP-binding proteins; lipid modification
of proteins. |
| Don Coltart |
Assistant Professor
of Chemistry |
Synthesis and methodology in the context of biologically relevant systems including secondary metabolites and glycopeptides possessing promising, unusual or unknown biological activity. |
| Alvin Crumbliss |
Professor
of Chemistry |
Biochemistry of iron, including transport, storage, oxidation-reduction,
molecular recognition, and the relationship
between iron and human health. |
| Michael
Fitzgerald |
Assistant
Professor of Chemistry |
Studies of protein folding and function using total chemical synthesis
and mass spectrometry-based approaches. |
| Katherine
Franz |
Assistant
Professor of Chemistry |
The confluence of inorganic, organic and biological chemistry, with particular
interests in the bioinorganic chemistry of
post-translational protein modifications and
the role of metal ions in neurochemistry. |
| Tim Haystead |
Associate
Professor of Pharmacology and Cancer Biology |
Development of proteomics technologies to probe signal transduction pathways
regulated by protein phosphatases and kinases
in vivo. |
| Homme Hellinga |
Professor of Biochemistry |
Combined theoretical and experimental approaches to protein and drug design;
molecular simulation; protein engineering. |
| Tao-shih Hsieh |
Professor
of Biochemistry |
Chromosome structure and function; structure, function, and mechanism of
DNA topoisomerase. |
| Donald McDonnell |
Professor
of Pharmacology
and Cancer Biology |
Development of and application of novel molecular approaches for the discovery of tissue specific modulators of steroid hormone receptors. |
| Thomas McIntosh |
Professor
of Cell
Biology |
Membrane structure; interactions between membrane surfaces. |
| George McLendon |
Professor
of Chemistry |
Protein chemistry: protein design, redox function, cellular control (apoptosis). |
| Anthony Means |
Professor
of Pharmacology
and Cancer Biology |
Intracellular signalling pathways that affect cell cycle progression; calcium receptor functions. |
| Paul Modrich |
Professor
of Biochemistry |
Mechanisms of DNA repair and DNA repair defects in tumor development. |
| Christopher Newgard |
Professor
of Pharmacology
and Cancer Biology |
A fundamental understanding of metabolic regulatory mechanisms, and in
the application of this understanding to the
development of new therapies for the epidemic
diseases of diabetes and obesity. |
| Michael Pirrung |
Professor of Chemistry |
Enzyme mechanism and inhibition, ethylene biosynthesis and action; combinatorial
chemistry; DNA chips. |
| Christian Raetz |
Professor
of Biochemistry |
Membrane biochemistry; molecular genetics of lipid metabolism in animal
cells; structure, biosynthesis, and function
in bacterial endotoxins. |
| Johannes Rudolph |
Assistant
Professor of Biochemistry |
Mechanistic enzymology; cell cycle regulation; protein phosphorylation. |
| Barbara R. Shaw |
Professor
of Chemistry |
Anti-sense DNA molecules; DNA sequencing technologies; mechanisms of mutations. |
| Tai-Ping Sun |
Associate Professor
of Biology |
Molecular genetics of plant growth hormones; environmental and developmental regulation of gibberellin biosynthesis and signal transduction. |
| Dennis Thiele |
Professor
of Pharmacology
and Cancer Biology |
Copper homeostasis in yeast and mammals; heat shock regulation.
|
| Eric J. Toone |
Professor of Chemistry |
Biocatalysis; protein-carbohydrate interaction; molecular recognition in
aqueous solution. |
| Ross Widenhoefer |
Assistant
Professor of Chemistry |
The development and mechanistic investigation of new organotransition metal-catalyzed
transformations for application to organic
synthesis. |
| John York |
Associate
Professor of Pharmacology
and Cancer Biology |
Structural and functional approach to understanding the role of inositol
signalling in human disease. |
